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What would you as buddhists, give as advice to my sister?

My sister suffers from a disease that causes her to be in chronic pain and feel constantly fatigued, I've been looking into Buddhism as a way to help myself. However I still can't find anything that could help with this condition, or a perspective to take on the situation. I know suffering comes from desire, but this seems like something rather extreme. I was just wondering if Buddhism may have any alternative views on her situation, many thanks :)

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